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Household dust is an important source of exposure to a lesser known – but ubiquitous and potentially toxic – flame retardant, reports a study from Belgium.
This study is the first to examine the relationship between dust, diet and serum concentrations of hexabromocyclododecanes (HBCDs). Results are consistent with studies of other better known flame retardants, indicating that indoor sources may contribute most of human exposure to these chemicals. 8 September 2009. More...
New experiments with combinations of contaminants shows that mixtures can cause harm even when the level of each chemical in the mixture would cause no effect by itself.
Because people are exposed to hundreds of chemicals at a time--or more--these results indicate that setting safety standards based on the action of individual chemicals will not be sufficient to protect human health. 1 September 2009. More...
The common and highly-used herbicide atrazine can act within the brain to disrupt the cascade of hormone signals needed to initiate ovulation, finds a new study.
The results shed new light on the way atrazine affects the female reproductive system and the persistence of these effects when adults are exposed. 20 August 2009. More...
Sperm counts are lower in mice whose mothers were exposed during pregnancy to a mixture of particles found in diesel exhaust.
The results add to a small but growing series of studies that suggest exposure to diesel exhaust can disrupt the proper development of the testis in rats and mice and perhaps affect reproduction. 14 August 2009. More...
A recent study links higher blood lead levels with high blood pressure in pregnant women, suggesting that lead exposure may increase the risk of developing hypertension during pregnancy.
All of the women in the study had blood levels below the level considered 'acceptable' by most health agencies, providing additional support for the need to lower the threshold. 10 August 2009. More...
A new study in Mexico finds that women with higher exposure to phthalates during their third trimester of pregnancy were up to four times as likely to have their babies early.
This is the first human study to investigate associations between exposure to phthalates and preterm birth rates. Early births are of concern because they are associated with long-term health problems and are the leading cause of neonatal mortality in the United States, accounting for more than one third of infant deaths. 3 August 2009. More...
Fish produced fewer – or no eggs at all – after only one to two weeks of exposure to either of two different types of synthetic progestin hormones found in women's birth control and menopausal drugs.
The more potent of the pair of progestins also lowered sperm production and affected behavior in male fish. Effects occurred at levels found in the environment in sewage effluents. 30 July 2009. More...
Women who are having difficulty conceiving may want to cut back on their soy consumption after a mouse study reveals that dietary exposure to genistein, a compound found in soy foods, can reduce the odds of a successful pregnancy in multiple ways.
The results reveal how natural compounds like genistein may have both risks – it can act as an endocrine disurptor to affect female reproduction – and benefits - such as protecting the heart. 28 July 2009. More...
Male rats reach puberty later and have skewed hormone levels after exposure to high concentrations of DEHP, a phthalate.
The researchers tested a wide range of DEHP levels in two different strains of rats and compared when the animals from the differen test groups hit puberty. The doses used – 10, 100, 300 and 900 milligrams per kilogram of rat body weight – are much higher than levels measured in people. 21 July 2009. More...
Scorpion venom can change the way rats grow and develop if they are exposed to the neurotoxins before birth.
Scorpion stings are a public health problem in Brazil. This is one of a few studies to date to examine if scorpion venom poses a unique threat to developing offspring. The study clearly shows that baby rats are developmentally altered in many ways if their moms are "stung" while pregnant. 15 July 2009. More...
A new study adds to the growing literature suggesting that chemical exposure may affect male fertility.
Men exposed to higher levels of contaminants produced by burning a range of substances, including coal, oil, gas and wood had an increased risk of infertility, according to results from a study conducted in China. 29 May 2009. More...
New research indicates that smoking during pregnancy can lead to impulsive behavior in children.
Preteenagers whose mothers smoked during pregnancy are more impulsive on a standard behavior test and use different regions of their brain while performing the test when compared to children whose mothers did not smoke. 26 May 2009. More...
Although there is a naturally wide range in the age that healthy girls enter puberty, a new study finds the age may be shifting younger for all of Denmark.
The shift toward a younger age is of concern because it exposes girls to hormones for more of their life and may lead to damaging behavioral changes. 26 May 2009. More...
Men with high levels of chemicals used as anti-adhesive, stain and water repellents had fewer normal sperms and a tendency for lower sperm concentration.
This study is the first to evaluate the potential impact of exposure to chemicals known as perfluoroalkyl acids, or perfluorinated compounds (PFCs), on male fertility. 7 May 2009. More...
Lead released from a woman's bones during pregnancy can affect her developing baby's DNA in ways that can alter gene expression and possibly increase the child's lifelong susceptibility to disease.
This is the first study to show that lead can influence genetic programming in human cells, and hence, gene expression, throughout life. 21 April 2009. More...
A study with mice finds that diet can modify the harmful effects of bisphenol A. The findings shed light on perceived inconsistencies in BPA research results.
Differences in diet dramatically altered the risk that mouse oocytes would develop errors in how chromosomes are aligned during cell division after exposure to BPA. When these errors occur in people, they can cause spontaneous miscarriage and severe disabilities. 9 April 2009. More...
Testosterone levels were significantly lower in men who lived in homes with high concentrations of flame retardants in house dust than those in homes with low levels of the chemicals in the dust.
The study of 24 adult men is the first to compare PBDE levels in dust with hormone levels in adult men. 1 April 2009. More...
Research using a powerful statistical model suggests that chemical mixes in wastewater feminize male fish.
Scientists in the United Kingdom report that more than one type of hormonally active chemical -- not just those that act like estrogen -- play a role in sex reversal of male fish. Anti-androgens also contribute. 2 March 2009. More...
A PCB mix altered reproductive hormones and organ growth in two generations of female rats that were never directly exposed to the chemicals themselves.
The abnormalities worsened in the granddaughters when compared to the daughters. The worst effects were seen at the mid -- not the highest or lowest -- level tested. Levels were within the range of human exposure. 27 February 2009. More...
More evidence from lab rat studies shows the plastic compound bisphenol A can permanently affect reproductive hormones, resulting in early puberty and odd ovulation patterns.
The study is the first to find long lasting hormonal changes when exposure occurs after birth, during critical times of development. Past studies have found similar effects when exposures occur before birth, during prenatal development. 19 February 2009. More...
Researchers report that very minute quantities of the hormone found in the birth control pill alter sperm development in rainbow trout by changing the number of chromosomes, which can lead to lower survival and long-term health problems in the offspring.
This error is called aneuploidy. For people, aneuploidy is the biggest known cause of spontaneous miscarriage and the number one cause of congenital birth defects. 17 February 2009. More...
Adult men with average amounts of phthalates in their urine had lower levels of two important hormones -- testosterone and estrogen -- in their blood.
This is the first study to show a relationship between phthalate levels and hormone levels in adult men. The phthalate levels "are representative of those found among the general US population," yet more research is needed to determine impacts on the men's health and fertility, say the authors. 27 January 2009. More...
A soy protein, genistein, long known to affect fertility, can change how pregnancies start and progress in female mice treated with it as newborns.
The changes make it harder for fertilized eggs to implant and grow, possibly contributing to infertility. The effects were observed at levels comparable to those experienced by human infants feeding on soy formula. 26 January 2009. More...
Pregnant women exposed to phthalates through hairspray and other sources at work have a greatly increased risk of delivering a son with a common reproductive birth defect known as hypospadias. Taking folate supplements might reduce this risk.
The findings from this British study of almost 1,000 infant boys highlights a new and compelling consequence of phthalate exposure and warrants increased caution in the workplace for pregnant women exposed to these chemicals. Phthalates are chemicals used in a wide variety of products including plastics, detergents and personal care products. 19 January 2009. More...
Women with potential exposure to pesticides at work or at home took longer to get pregnant than women without pesticide connections.
The findings agree with past studies and add more evidence to this sometimes confusing mix of research outcomes. 15 January 2009. More...
Research with mice reveals that the phthalate DEHP can increase the severity of allergic reactions in young animals when they are exposed neonatally to the contaminant via their mother's milk.
Rates of allergic skin conditions -- called dermitits -- are increasing in people. These new results may shed light on one of the drivers of this trend. 14 January 2009. More...
In this first study examining infants’ exposure to bisphenol A, premature babies hospitalized in neonatal intensive care units had levels of BPA in their urine 10 times higher than the general population.
The source of exposure most likely was plastic medical devices used in the hospital, although some could have come from infant formula. BPA is a plastic compound that is linked to various health abnormalities in humans and lab animals. 12 January 2009. More...
Eating a mix of soy compounds may be a safer way than traditional hormone therapies to protect against age-related brain disease, finds a new study that tested the mixtures in rats.
That's what scientists from the University of Southern California report from experiments in which they tested the effects of a combination of natural estrogen-like compounds. The mixture protected aging rat brains against disease without causing some of the reproductive-side effects that accompany the use of hormone replacement therapy (HRT). 24 December 2008. More...
Women living in areas with heavy traffic flow are 1.5 times more likely to lose their babies during late gestation or have their newborns die compared to those who live in areas with less traffic, according to a Brazilian study.
The findings implicate air pollution, but confounding effects of other factors cannot be ruled out. 18 November 2008. More...
In a unique study, researchers show that exposure to PCBs in rats interferes with learning by stopping the brain from forming complex nerve networks essential for memory and intellect.
This effect could underpin some of the impacts that PCBs have on children's ability to learn. 7 November 2008. More...
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